★Article of Professor Nishiyasu, Assistant professor Fujii and Ph. D. student Katagiri was published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
An article by Akira Katagiri, Professor Takeshi Nishiyasu, and Assistant Professor Naoto Fujii was published in the international journal, “American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.”
In exercising humans, once the core temperature reaches ~37°C, minute ventilation increases linearly with rising core temperature, and the slope of the relation between ventilation and core temperature reflects the sensitivity of the response. This hyperthermia-induced hyperventilation may be a contributing factor in the decreased exercise performance in the heat, or even in the development of heatstroke. This study suggested that sodium bicarbonate ingestion, which increases arterial pH, does not alter the core temperature threshold or sensitivity of hyperthermia-induced hyperventilation during prolonged exercise in the heat; instead, it downshifts the exercise hyperpnea. It is expected that the result of this research will provide new insight into the development of effective strategies for attenuating hyperthermia-induced hyperventilation and averting heatstroke.
【Title】 Sodium bicarbonate reduces ventilation without altering core temperature threshold or sensitivity of hyperthermia-
induced hyperventilation in exercising humans
【Authors】 Akira Katagiri, Naoto Fujii, Kohei Dobashi, Yin-Feng Lai, Bun Tsuji, Takeshi Nishiyasu
【Journal】 American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
【DOI】 10.1152/ajpregu.00282.2022
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology