★Article of Professor Nishiyasu, Associate professor Fujii and Dr. Katagiri was published in the American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Hyperthermia leads to hyperventilation and associated cerebral hypoperfusion, both of which may impair heat tolerance. This hyperthermia-induced hyperventilation may be mediated by peripheral chemoreceptors which can be activated by reductions in arterial pH. However, our results suggest that sodium bicarbonate ingestion, which can increase arterial pH, is not have a potential benefit in alleviating hyperthermia-induced hyperventilation and cerebral hypoperfusion in resting heated humans. Future studies are required to delineate other interventions that can effectively alleviate hyperthermia-induced hyperventilation and cerebral hypoperfusion in resting heated humans.
【Title】 Effects of sodium bicarbonate ingestion on ventilatory and cerebrovascular responses in resting heated humans
【Authors】 Akira Katagiri, Naoto Fujii, Kohei Dobashi, Yin-Feng Lai, Bun Tsuji, Takeshi Nishiyasu
【Journal】 American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
【DOI】 10.1152/ajpregu.00161.2024
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology